New Lyme Test
This new single-tier point-of-care test for Lyme disease, a synthetic peptide-based multiplexed vertical flow assay (xVFA) with results available in 20 minutes, sounds somewhat promising. Early results show 95.5% sensitivity and 100% specificity in a separate validation cohort from the Lyme Disease Biobank. There was some limited evidence that it was effective in detecting disease within 1-4 weeks from what was thought to be the incident tick bite. One question I have is whether there will be a way for the testing to determine acute versus previous Lyme disease, and what the false positive rate might be for patients with a past history of Lyme. More testing required, original article published August 20 in nature communications.