Medscape Newsfeed:
- New COVID Variant of Concern Drives US Travel Bans
WHO has labeled a new variant from South Africa as a variant of concern, prompting new travel restrictions from that country and others starting November 29. Medscape Medical News
- Should Everyone Get a COVID-19 Vaccine Booster?
France has just made boosters available for everyone over 18, as long as it has been 5 months since their second dose. Those who are not vaccinated by mid-January risk losing their pass sanitaire. Medscape Medical News
- Triplet Regimen Boosts Survival in Metastatic Melanoma, but at a Cost
For patients with metastatic melanoma, triplet therapy with atezolizumab and vemurafenib plus cobimetinib provides significant survival benefits, but the regimen may not be cost-effective, researchers say. Reuters Health Information
- Maintenance Olaparib Benefits Sustained Beyond 2 Years Treatment
Women with newly diagnosed ovarian cancer and a BRCA mutation see sustained benefits in progression free survival rates after two years of maintenance olaparib therapy, a clinical trial analysis suggests. Reuters Health Information
- Nadolol Noninferior to Propranolol for Infantile Hemangiomas: Study
'Further studies are needed to prove superiority over propranolol,' say the study authors. Medscape Medical News
NIH Newsfeed:
- Repurposed ALS drug shows promise in mouse model of rare childhood genetic disorder
NPC1 leads to difficulty controlling movements, liver and lung disease, impaired swallowing, intellectual decline and death.
- Lung autopsies of COVID-19 patients reveal treatment clues
SARS-CoV-2 prevents lung tissue repair, regeneration.
- Persistent, distressing psychotic-like experiences associated with impairment in youth
NIH-funded study highlights the need for early intervention and support for youth who report these experiences.
- Long-term study of children with COVID-19 begins
NIH-supported research will track effects of COVID-19 infection on children over three years.
EM Journal Watch Newsfeed:
- New Surviving Sepsis Guidelines
In this update, recommendations include using balanced crystalloid for resuscitation and steroids for persistent shock.
- Medication Harms Leading to Emergency Department Visits
The U.S. CDC reports national data on medication-related adverse events leading to emergent care.
- Early CT Angiography for Suspected Acute Coronary Syndromes
Early computed tomographic angiography did not change outcomes at 1 year.
- Racial Disparities in Clinical Medicine
An NEJM Group eBook explores how racial inequity persists in clinical medicine and what we can do to begin to counter it.
- EPIC's Sepsis Model Is Not Ready for Prime Time
Despite its widespread use, the proprietary electronic health record system missed sepsis 67% of the time.