Medscape Newsfeed:
- Sweeteners Transform Both Weight Loss and Gut Health
Replacing sugars with sweeteners and sweetness enhancers supported weight loss maintenance and improved gut microbiota composition in adults with overweight or obesity over 1 year. Medscape Medical News
- UK Regulator Targets Delays in Rare Disease Treatments
The MHRA plans a flexible new framework to speed up access to treatments for rare diseases, addressing long delays and complex regulatory hurdles. Medscape News UK
- Self-Injected Med Shows Rapid, Sustained Benefit in gMG
Topline phase 3 results show that the novel nanobody gefurulimab is safe and effective for AChR-antibody-positive myasthenia gravis, but long-term results will be key. Medscape Medical News
- Systemic Therapy for Sjögren Closer With Phase 3 Success
Current treatment options have been limited to symptom control. Telitacicept, a novel fusion protein, and ianalumab, a monoclonal antibody, demonstrate improvement in disease activity. Medscape Medical News
- ‘Energy Insecurity’ Tied to Anxiety, Depression Risk
Difficulties with paying for household energy needs is linked to increased risk for both anxiety and depression in US adults, a new study suggests. Medscape Medical News
NIH Newsfeed:
- HHS Doubles AI-Backed Childhood Cancer Research Funding
Following an Executive Order by President Trump, HHS will increase funding of data-centered pediatric cancer research.
- Secretary Kennedy Swears in Dr. Anthony Letai as Director of the National Cancer Institute
Dr. Letai will serve as NCI’s 18th director.
- NIH establishes nation's first dedicated organoid development center to reduce reliance on animal modeling
The Standardized Organoid Modeling Center aims to produce standardized protocols for organoid research, addressing reproducibility challenges.
- NIH launches $50M Autism Data Science Initiative to unlock causes and improve outcomes
Funded projects will drive discoveries across biology, environment, and autism services.
EM Journal Watch Newsfeed:
- Vasopressor Initiation via Peripheral IV: Current Practice, Outcomes
Patients with sepsis who received vasopressors peripherally had few complications and no increase in mortality.
- How Can We Reduce Asthma Exacerbations in Pregnancy?
Continue preventive asthma therapy during pregnancy to lower exacerbation risk.
- Are Multiple Doses of Ondansetron Beneficial for Gastroenteritis in Children?
This strategy reduced the severity of gastroenteritis and was safe overall, with diarrhea being the main side effect.
- Trends in Placement of PEG Tubes in Patients with Acute Ischemic Stroke
In recent years, percutaneous endoscopic gastrostomy has been performed less commonly in these patients.
- Can POCUS Improve Rhythm Identification and Outcomes in Out-of-Hospital Cardiac Arrests?
Point-of-care ultrasound early in cardiac arrest detected previously unidentified shockable rhythms, but outcomes didn't improve.