A large and nicely done (matched sibling to reduce confounding)  study from Hong Kong by Luo S, Gong Q, Ai Y, et al. adds more reassurance to the safety of acetaminophen in pregnancy.  From the study’s key points:

“Question  Does prenatal exposure to paracetamol (acetaminophen) increase the risk of autism spectrum disorder (ASD) or attention-deficit/hyperactivity disorder (ADHD) in offspring after accounting for unmeasured familial confounding?

Findings  From an initial cohort of 708 020 mother-child pairs in Hong Kong (approximately 43.3% with prenatal paracetamol exposure), a sibling-matched cohort was constructed of 124 333 children who were assessed for ASD and 97 285 for ADHD. Prenatal paracetamol exposure was not associated with an increased risk of either ASD or ADHD and these findings were consistent across paracetamol exposure timing, pattern, and dose.”

Here are two medicine-relevant papers that I found very interesting.  The first discusses the work being done on the development of a fentanyl vaccine in the hope of decreasing the tragic death toll from its non-medical use.  The second is from Eric Topol’s terrific Ground Truths Substack where he talks about two recent papers, one from Germany and the other from Google in Cal, both looking at the performance of agentic AIs compared against clinicians.  Both were text based (not verbal) interactions, one with an agent presenting real world HPIs and the other with patient actors — and so decidedly not real world scenarios. Nevertheless, in both cases the AI agents outperformed real world physicians.  Read Topol’s post for his excellent summary, cautions, and analysis.

• Schweitzer K. Inside the Push for a Fentanyl Vaccine. JAMA. Published online June 12, 2026. doi:10.1001/jama.2026.6392

• Eric Topol’s Agentic AI Comes to Medicine here: https://jamanetwork.com/journals/jama/fullarticle/2850522

From “There Has Never Been an Example of Presidential Corruption Like This” — a May 20, 2026 NY Times editorial:

“Congress and the executive branch built rules and traditions to ensure that federal agencies, especially the Justice Department, operated in the public interest, rather than that of the president. Mr. Trump has tried to break this system. Once he is gone, it will need to be rebuilt, and better than before. He has exposed and exploited its flaws and gaps. Unless they are filled, Mr. Trump’s corruption and perversion of justice risk becoming the norm.

In the meantime, Americans should be cleareyed about what the president is doing. He is taking their money and showering it on criminals.”

Yup.

This is a pretty interesting paper published in the April 30 edition of Science ( Peter G. Brodeur et al., Performance of a large language model on the reasoning tasks of a physician. Science 392,524-527 (2026). DOI:10.1126/science.adz4433 ).

Excerpts from the article: